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The 100+ lab panel

Get a deep, data-driven picture of your health. Your annual membership includes a clinically curated panel of biomarkers for the most comprehensive insights.

Heart Health

Stress & Aging

Hormonal Health

Metabolic Health

Nutrients, Vitamins & Minerals

Inflammation & Immunity

Liver Health

Kidney Health

Blood Health

Urine Analysis

Heart Health

Measures the ratio of total cholesterol levels to high-density lipoprotein cholesterol (HDL).

The TG:HDL-C ratio is a calculated marker derived from dividing triglyceride (TG) levels by high-density lipoprotein cholesterol (HDL-C) levels. This ratio is used as an indicator of cardiovascular and metabolic health, particularly insulin sensitivity

ApoB helps transport lipids throughout the bloodstream which is vital to the health of cardiovascular function. Along with other lipid tests ApoB is a powerful risk marker for cardiovascular disease.

This ratio refines cardiovascular risk assessment by comparing “bad” LDL cholesterol to apolipoprotein B (Apo B), which represents the number of atherogenic lipoprotein particles. Maintaining a favorable LDL / Apo B ratio can help protect against plaque buildup and heart disease.

HDL is part of a comprehensive lipid panel, an essential risk assessment for heart disease. There are two types of cholesterol: high-density lipoprotein (HDL) and low-density lipoprotein (LDL). Think of the H as healthy, helpful, heart-supporting cholesterol that helps reduce plaque buildup.

CRP is a protein released by the liver in response to inflammation. Elevated levels can indicate infections or chronic inflammatory conditions. Tracking CRP helps identify underlying inflammation and monitor disease progression or treatment effectiveness.

Refers to the most common or average size of LDL particles in your blood. This is important because smaller LDL particles are more likely to contribute to plaque buildup in arteries, increasing the risk of cardiovascular disease.

This test is a risk marker for cardiovascular diseases. LDL is responsible for carrying cholesterol to cells. However, despite its good intentions, LDL is known as the “bad” cholesterol because, when levels are too high, it can cause the formation of plaque buildup in the arteries.

hs-CRP is revelatory in one's overall health as it relates to the risk of inflammation-related diseases. Chronic inflammation is linked to every major disease: heart disease (even before symptoms occur), type 2 diabetes, cancer, high blood pressure, Alzheimer’s, depression, all autoimmune diseases, and severe allergic reactions like asthma.

Total cholesterol numbers are part of a risk assessment for heart disease. Too much cholesterol in the blood can damage arteries and blood vessels and elevate the risk for stroke, heart attack, and heart disease. Cholesterol is a fatty substance produced by the liver to help with thousands of bodily functions, such as building cells, promoting hormone and brain function, and synthesizing vitamin D.

The ratio of triglycerides to HDL measures risk for heart disease. Triglycerides are the most common type of fat in the body that stores excess energy from one's diet. An accumulation of triglycerides means there is too much fat in the blood and may indicate higher risk of a cardiac event.

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Stress & Aging

Cortisol, for one, is often referred to as “the stress hormone.” However, it goes beyond stress to help the body with numerous functions. Testing can detect imbalances in adrenal function.

DHEA Sulfate, the most abundant hormone in the human body, is associated with longevity, positive reproductive outcomes, and immune system regulation. This test can gauge reproductive function and the health of your adrenal gland.

Biological age reflects how one's body is aging at the cellular and molecular levels, which can determine the risk of age-related conditions like cardiovascular diseases and cognitive decline. Unlike calendar age (number of years lived), biological age is reversible and something one can optimize. It calculates mortality risk and phenotypic age based on various lab test results. While biological age on its own might seem like a vanity metric, when combined with 100+ lab tests, it offers a comprehensive benchmark for tracking and enhancing health and longevity.

Hormonal Health

PTH is secreted by the parathyroid glands to regulate calcium and phosphate levels. Abnormal PTH can point to issues with bone health, kidney function, or vitamin D metabolism, making this test essential for assessing mineral balance and overall skeletal integrity.

In all adults, healthy levels of testosterone are important for general health, body composition, sexual function, and reduced risk of disease. Kyma tests both "free" and “total” testosterone in the blood.

When SHBG levels change, it can impact the amount of available hormones in the body, either too much or too little. This can impact sexual function and fertility. SHBG patrols the amount of sex hormones the body tissues can use.

T3 levels can reveal an overactive (hyperthyroidism) or underactive (hypothyroidism or Hashimoto’s) thyroid. T3 is the most powerful thyroid hormone in the body. It helps regulate body temperature, control heart rate, lower cholesterol, improve memory, promote regrowth after hair loss, soothe muscle aches, regulate bowel movements, and support fertility.

Triggers key reproductive functions, such as ovulation in women and testosterone production in men.

Helps regulate reproductive processes by promoting the growth of eggs in ovaries or sperm in testes, making it essential for fertility.

The free androgen index (FAI) is a calculation used to estimate active, unbound male hormones (androgens) in the bloodstream. It helps evaluate hormone balance affecting fertility, sexual function, muscle mass, and energy levels in both men and women.

About 1 in 5 women and 1 in 10 men have hypothyroidism, and a TSH test can help reveal thyroid issues. Looking at abnormal TSH results alongside thyroid peroxidase (TPO) may be a sign of Graves’ disease. TSH is produced by the pituitary gland and controls the release of thyroid hormones: triiodothyronine (T3) and thyroxine (T4).

This test is typically cross-referenced with TSH and T3 to gain insight into overall thyroid function. Thyroxine, or T4, is produced in the thyroid then released into the bloodstream where it travels to the liver and kidneys. It is converted into the hormone triiodothyronine (T3). The synergy of T4 and T3 is important for heart and digestive function, metabolism, brain development, bone health, and muscle control.

This helps evaluate functions associated with testosterone levels, such as fertility, sexual function, muscle mass, energy, mood, insulin resistance/sensitivity, and pituitary function. It can also screen for prediabetes. Kyma tests both "free" and “total” testosterone in the blood.

Used to assess pregnancy viability, as well as to evaluate function in reproductive health.

A form of estrogen, a hormone that plays a key role in female reproductive health and menstrual cycle regulation.

Metabolic Health

Insulin levels can uncover reasons behind abnormal blood sugar, insulin resistance, and more. It can also reveal hidden blood sugar issues even years before they escalate to something like diabetes. Establishing one's insulin baseline can be incredibly insightful to how one's lifestyle affects health.

HOMA-IR is an estimate of insulin resistance calculated from your paired glucose and insulin blood test results.

Uric acid in the blood screens for metabolic disorders, like gout, anemia, and immunodeficiencies. This often overlooked test has renewed attention after recent studies show elevated levels can increase the risk of death from cardiovascular issues by 39% and stroke by 35%.

HbA1c is the average amount of glucose attached to blood cells over the last 90 days. It diagnoses, monitors, and screens for prediabetes and diabetes. This test is a revelatory look into one's health, specifically the body’s ability to control blood sugar. Unhealthy levels are triggered by inflammation, vitamin deficiencies, kidney damage, thyroid disorders, and more. One's diet and habits can have a substantial impact on this test.

Too much glucose (hyperglycemia) is a major driver of many diseases and illnesses, including cancer, diabetes, high blood pressure, heart attacks, kidney disease, and Alzheimer’s disease. Glucose is a type of sugar (from food) that the body uses for energy. When glucose is not absorbed and used, it can form glycogen and be stored as fat in the liver. Over time, this can lead to a decline in overall health.

Nutrients, Vitamins & Minerals

While omega-6 is typically higher than omega-3, ensuring that this ratio remains low is important.

Omega-3 fatty acids, including EPA and DHA, are essential for reducing inflammation, supporting heart health, and promoting brain function. This test is important because adequate omega-3 levels are associated with a lower risk of heart disease, better inflammatory response, and improved mental health.

Vitamin B12 is integral for nerve function, DNA synthesis, and red blood cell formation. Testing helps identify deficiencies linked to fatigue, neurological symptoms, and anemia.

Healthy iron levels create vitality throughout the entire body. Iron helps various vital functions, like providing energy and focus, building a strong gastrointestinal tract and immune system, and regulating body temperature. Iron deficiency can lead to numerous biological problems, including anemia.

Folate (vitamin B9) is essential for DNA synthesis, red blood cell production, and preventing neural tube birth defects. Testing helps identify deficiencies that may impact energy, mood, or cardiovascular health.

Corrected calcium is a calculated measure of blood calcium that adjusts for variations in albumin levels. The corrected calcium calculation adjusts for this discrepancy, providing a more accurate assessment of the body’s "free" or ionized calcium, which is essential for muscle function, nerve signalling, and bone health. Corrected calcium is particularly useful for people with conditions that alter albumin levels, such as liver disease, kidney disease, or malnutrition, as it reflects a more accurate calcium status in the bloodstream despite fluctuating protein levels.

Imbalanced omega-3 and omega-6 levels are a risk factor for cardiovascular disease, age-related macular degeneration, rheumatoid arthritis, cancer, and more. Omegas are essential fatty acids (EFAs), which are the building blocks for every cell in the body. Well-balanced omegas can contribute to optimal brain performance, mental health, nerve function, a healthy heart, circulation, immune system, gastrointestinal tract, skin, hair, and nails.

Vitamin D deficiency is widely underdiagnosed and undertreated. Over time, low levels can lead to hypothyroidism, osteoporosis, cancer, heart disease, fatigue, depression, seasonal affective disorder (SAD), gut issues, and fibromyalgia. The role of vitamin D is vast and benefits the immune system, thyroid, bones and teeth, muscles, and brain.

Magnesium is a mineral imperative for cells to make energy, for chemical pumps to work and stabilize membranes, to help muscles relax, and so much more.

A homocysteine test checks the body’s vitamin B levels and methylation function, a key biochemical process essential for almost all of the body’s systems. Abnormal homocysteine can build up and increase the risk of blood clots, dementia, osteoporosis, heart disease, heart attack, and stroke. Homocysteine is an amino acid that helps organs grow and regenerate.

Reflects your body’s iron stores, giving insight into whether you have too much or too little iron.

Calcium levels help understand symptoms related to the kidneys, bones, thyroid, parathyroid, or nerves. Calcium is a mineral the body uses to build and maintain strong bones, teeth, muscle control, and blood circulation.

Inflammation & Immunity

LDH is an enzyme found throughout the body that helps convert sugar into usable energy. Elevated levels may signal tissue damage, hemolysis, or other health concerns, highlighting the importance of LDH in diagnosing various conditions.

Testing the quantity of neutrophils helps detect damage caused by inflammatory disorders (such as rheumatoid arthritis and gout), infections (both acute and chronic), certain cancers (such as myelocytic leukemia), and physical stressors (including eclampsia in pregnant women, injury, and burns). Neutrophils are key patrols and first responders in the immune system, attacking antigens they encounter. The test includes both percentage and absolute levels.

Lymphocyte levels can reveal a number of conditions, including autoimmunity, bone marrow disorders, kidney disease, gastrointestinal disorders, and more. The role of lymphocytes in the body’s immune defense is so crucial that abnormal levels can weaken the body, leading to severe illness or impairing its ability to fight off infections. The test includes both percentage and absolute levels.

Eosinophils are recruited to inflamed areas of the body to trap substances, kill infected cells, viruses, parasites, and bacteria, and help tame an allergic response. Testing can reveal issues in the digestive tract, specifically the esophagus, and includes both percentage and absolute levels.

A healthy WBC baseline over time correlates with the body's ability to fight off diseases and other hazards. Prolonged abnormalities can negatively affect biological age by impairing healing and increasing the risk of illness.

Like other white blood cells (WBCs), monocytes help the immune system destroy invaders and also facilitate healing and repair. Abnormal levels can indicate bacterial infections, virus or fungus, stress, chronic infections, or autoimmune disorders. The test includes both percentage and absolute levels.

Non-specific marker used to detect inflammation in the body; a blood test that measures how quickly erythrocytes (red blood cells) settle at the bottom of a test tube over a specified period.

Basophils account for only around 1% of white blood cells but play a role in allergy defense and stimulate antibodies against pathogens and parasitic organisms (such as ticks and worms) that cause injury or infection.

Liver Health

Globulin is a protein essential for liver function, blood clotting, and immune system operations. Abnormal globulin levels can indicate various conditions, such as liver disease, autoimmune disorders, or chronic infections.

In tandem with a full liver panel, this test can help determine the cause of jaundice and/or help diagnose conditions such as liver disease, hemolytic anemia, or blockage of the bile ducts. The liver makes bile to help digest food, and bile contains bilirubin. A healthy liver can get rid of bilirubin, but when the liver isn't working properly, it cannot break down bilirubin and dispose of it.

ALP can help detect and/or monitor conditions related to the liver, malnutrition, autoimmune disorders, or bone disease. ALP is an enzyme that breaks down proteins. It is found throughout the entire body, but is mostly prevalent in the liver, bones, intestines, and kidneys.

A protein made by the liver that helps maintain fluid balance in your body and transport essential substances in the blood.

Measures the combined levels of proteins in your blood, including albumin and globulin, which are essential for immune function and overall health.

Monitor liver health with GGT. This test helps detect liver disease, identify bile duct blockages, and check for conditions related to alcohol and toxins. The GGT biomarker is a reliable detector (but not a diagnostic test) for toxin exposure or fatty liver from alcohol, even when other liver tests are normal.

AST is an enzyme mostly found in the liver and helps metabolize amino acids. Testing for AST in the blood can help detect liver damage from injury or a number of diseases and conditions, like hepatitis, cirrhosis, mononucleosis, or other liver diseases, heart problems, or pancreatitis.

The A/G ratio, or albumin/globulin ratio, is a measure of the relative levels of albumin and globulin proteins in the blood. Albumin is a protein produced by the liver that helps maintain fluid balance in the blood and transports various substances such as hormones and fatty acids. Globulins, on the other hand, encompass a diverse group of proteins, including antibodies, enzymes, and transport proteins. The A/G ratio reflects the balance between albumin and globulin proteins in the blood.

ALT is an enzyme that checks on liver health. If one's liver cells are damaged due to excess alcohol, drugs, disease, or injury, ALT will appear in the bloodstream and, therefore, in a blood test.

Kidney Health

Keep an eye on kidney health with microalbumin. This test checks for small fragments of albumin in one's urine, which may be an early indication of kidney damage due to hypertension or type 2 diabetes. Microalbumin will show issues even before the normal kidney tests (creatinine and BUN) are elevated.

Urine creatinine is a waste product resulting from the normal breakdown of muscle tissue. The kidneys filter creatinine out of the blood, and it is excreted in the urine. Measuring creatinine in urine is commonly done to assess kidney function, often as part of a urine creatinine clearance test, which compares creatinine levels in both blood and urine to evaluate how effectively the kidneys are filtering.

A sodium test looks at electrolytes and pH. When sodium levels are abnormal, it can signal issues with the brain, lungs, liver, heart, kidneys, thyroid, and adrenal glands.

Estimates how well your kidneys are filtering waste from your blood, with lower values indicating reduced kidney function.

Creatinine levels vary from person to person, but abnormalities typically signal kidney disease or damage. One's creatinine levels are directly related to lifestyle, diet, medication, and how those can impact the kidneys’ ability to function. Creatinine (not to be confused with creatine) is a chemical compound left over from everyday wear and tear of the muscles.

Urea nitrogen is a waste product that the kidneys flush out, but the presence or buildup of urea nitrogen waste in the blood means the kidneys aren't regulating waste properly. Compared to one's creatinine levels, this test can screen for kidney disease.

Urea is a waste product produced when the liver breaks down proteins. The kidneys normally filter urea out of the blood, so measuring its levels is a key indicator of kidney function. Elevated urea may suggest reduced kidney efficiency or dehydration.

The Urine Albumin/Creatinine Ratio (UACR) measures the amount of albumin (a type of protein) in your urine relative to the amount of creatinine. This ratio helps account for variations in urine concentration, providing a more accurate assessment of albumin excretion compared to albumin concentration alone.

Potassium levels can detect kidney disease, liver disease, heart failure, high blood pressure, or other disorders. As an electrolyte, potassium helps muscles contract, aids digestion, allows nerves to transport messages from the brain to the body, and balances fluids and regulates blood pressure.

Cystatin C is a small protein found throughout our entire body and is also filtered out through the kidneys. It is not affected by diet or muscle mass but can be affected in obesity, low thyroid hormones and when certain medications are used. Measuring kidney function with both creatinine and cystatin C thus provides a more accurate estimate of kidney function.

A chloride test is useful in diagnosing the underlying causes of abnormal fluid levels or pH balances, such as dehydration, kidney disease, liver disease, heart failure, high blood pressure, or other disorders. Chloride is a major mineral in the body that manufactures channels in cell membranes, which carry out different vital tasks.

This ratio helps evaluate kidney function and can indicate conditions such as dehydration, kidney disease, or issues affecting kidney perfusion. A high ratio may suggest dehydration or upper gastrointestinal bleeding, while a low ratio can point to acute tubular necrosis or liver disease.

Blood Health

Red blood cells carry oxygen from the lungs to the rest of the body and return carbon dioxide for exhalation. This test helps detect conditions such as anemia, dehydration, and polycythemia. Abnormal RBC levels can indicate various health issues, including nutritional deficiencies, bone marrow disorders, and chronic illnesses.

Nucleated Red Blood Cells (NRBCs) are immature red blood cells that still contain a nucleus. Normally, these cells mature in the bone marrow and lose their nucleus before entering the bloodstream. NRBCs are usually absent in the peripheral blood of healthy adults and are typically only found in the bloodstream of fetuses and newborns.

MCHC measures the amount of hemoglobin per unit volume. So, this test assesses the hemoglobin content within the volume of the cell, which can uncover iron-deficiency anemia, hypothyroidism, spherocytosis, or RBC agglutination.

Hemoglobin reflects the number of red blood cells active in the blood. Low levels may uncover anemia, vitamin deficiencies, loss of blood (both internal and external), and chronic diseases. The test can also help detect diseases affecting the lungs, liver, kidneys, or cardiovascular system, significant long-term infection, cognitive impairment, and certain types of cancer, and diagnose chronic blood disorders.

RDW is the size and volume of the red blood cells. RDW and MCV explore one's overall health, and together, they can detect liver disease and various types of vitamin-deficiency anemias even before symptoms occur. When either or both are abnormal over time, it can lead to a higher risk of disease and increase one's phenotypic age.

Abnormal platelet count is a risk marker for heart attack, stroke, and other heart diseases, but this test can also help diagnose autoimmune disease, bone marrow damage (which can be caused by certain cancers, such as leukemia and/or cancer treatments), spleen disorder, and parasites. Platelets, which are made in the bone marrow, are small, colorless blood cells that form clots with the goal of stopping or preventing bleeding.

MCV's insight into the blood is a unique indicator of overall health. If MCV is either high or low overtime (most likely indicating a chronic vitamin deficiency or blood condition), it can degrade the body's general wellness and thus one's phenotypic age. MCV measures average size of red blood cells: whether they are too big, too small, or just right

MCH is usually done as part of the complete blood count and can help detect various types of anemia (deficiency in iron, B12, or folate), blood loss, cancer, kidney or liver disease, or autoimmunity. MCH measures the average amount of hemoglobin in the red blood cells.

As part of the complete blood count, an HCT test measures the percentage of red blood cells in the blood. This test helps screen for, diagnose, and monitor conditions that affect the blood or bone marrow.

Urine Analysis

Urine pH measures the acidity or alkalinity of urine, reflecting how well the kidneys are balancing water and excreting waste.

Urine red blood cells (RBCs) are red blood cells that appear in the urine. Normally, the kidneys prevent RBCs from entering urine, so their presence in a urinalysis typically signals a disruption in the filtration barrier or another issue along the urinary tract.

Urine color and appearance refer to the visual characteristics of urine, including its color ranging from clear to dark yellow or even unusual hues and any visible abnormalities such as cloudiness or sediment.

A substance that is commonly measured in urine as part of a urinalysis.

Casts, Crystals, Mucus refers to elements that can be found in a urine sample during a urinalysis. These substances can indicate various aspects of kidney function, urinary health, and metabolic conditions. Casts are cylindrical structures formed from proteins in the kidney tubules, crystals are solid forms of mineral salts that may precipitate in the urine, and mucus can originate from the urinary tract lining. Their presence and levels in urine can provide information on underlying health conditions or urinary tract issues.

Bilirubin and urobilinogen are byproducts of the body’s breakdown of red blood cells. Bilirubin is produced in the liver when hemoglobin from old red blood cells is broken down, and it is normally processed by the liver and excreted in bile.

Specific gravity assesses the concentration of acidity or alkalinity, reflecting how well the kidneys are balancing water and excreting waste

Urine white blood cells (WBCs) are immune cells that typically appear in urine when there is inflammation, infection, or another form of immune response in the urinary tract. Under normal circumstances, only a minimal number of WBCs should be present in the urine.

Urine epithelial cells are cells from various parts of the urinary tract that are naturally shed into the urine. These cells include non-renal epithelial cells, which originate from the urethra, bladder, or genital areas, and renal epithelial cells, which come specifically from the kidney tubules.

A substance that is commonly measured in urine as part of a urinalysis.

Occult blood refers to the presence of hidden blood in bodily substances, often tested in stool or urine samples. Occult blood isn’t visible to the naked eye but can be detected through specific tests, such as the fecal occult blood test (FOBT) or urine dipstick test. The presence of occult blood may indicate bleeding somewhere in the digestive or urinary tract.

Urobilinogen is formed in the intestines as bacteria act on bilirubin, with some urobilinogen excreted in the urine and some in the stool.

Bacteria, Yeast, Trichomonas refers to common microorganisms that may be detected in a urinalysis or a vaginal swab test. These organisms are often tested to identify infections or imbalances in the body, especially in the urinary or reproductive systems. Bacteria can indicate bacterial infections, yeast is commonly linked to fungal infections like candidiasis, and Trichomonas is a protozoan parasite responsible for trichomoniasis, a sexually transmitted infection (STI).

Did you know?

The average annual check-up tests only 19 biomarkers

Kyma includes over 100 biomarkers to give you the most complete picture of your health

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The 100+ lab panel

Heart Health

Cholesterol / HDL Ratio

TG:HDL-C Ratio

Apolipoprotein B (Apo B)

LDL Cholesterol

HDL Cholesterol

C-Reactive Protein (CRP)

Estimated LDL particle size

LDL / Apo B Ratio

High-Sensitivity C-Reactive Protein (hs-CRP)

Total Cholesterol

Triglycerides

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